The Microscan system is a handheld video microscope, that uses the SDF technique to visualise microcirculation in patients at the bed side. Find out more here about its specifications and usage.
The MicroScan Video Microscope system allows physicians to assess the microcirculation real time of the patient at the bed side. It is the world wide standard for clinical microcirculation assessment at the bed side.
It has been used in over 200 clinical publications in peer reviewed medical journals. Our validated real time Automated Vascular Analysis software provides the user all scores dictated by the international microcirculation assessment consensus meeting. The MicroScan system is the only CE certified hand held device incorporating SDF technology with which physicians can assess the microcirculatory perfusion of their patients at the bed side. This certification is awarded after the MicroScan system has been rigorously inspected, tested and released. The MicroScan system makes use of sterilised disposables that have been tested, validated and cleared for clinical use. The MicroScan system is battery operated meaning that the physician can assess the microcirculation without having to rely on available power outlets whilst providing additional safety for the patient using a low current. Additionally the MicroScan makes use of a USB interface connecting with which it can be safely connected to any laptop using an Intel i5 processor or higher. The MicroScan system is a hand held video microscope using green LED illumination (550 nm). It is available in 5x magnification allowing a field of view of 0.94 mm x 0.75 mm at a resolution of 720×576 pixels.
The MicroScan Video Microscope System consists of:
Our new research software provides the user all scores dictated by the international microcirculation assessment consensus meeting. The new Automated Vascular Analysis 4.0 research software, is a completely revolutionised microcirculatory image analysis software which can be used for the MicroScan System. A real time video of AVA 4.0 can be viewed here. The first full version of our research software will be released in September 2014 at the ESICM meeting in Barcelona. The key features of this new research software are:
There is currently no other analysis tool available that can fully automatically analyse microcirculatory images.
Here you find the latest articles on microcirculation & the use of the SDF technique. If you are looking for articles in a specific field of interest you can contact us here.
Semin Respir Crit Care Med. 2011 Oct;32(5):558-68. Abstract Largely ignored throughout the history of clinical medicine, the microcirculation has recently been recognized at the bedside as the center of several pathophysiological processes. Normal microcirculatory function is critical for adequate tissue oxygenation and organ function, but it has a poorly understood and highly heterogeneous structure that is related to the diversity of functions that it accomplishes. The most important function of the microcirculation is the regulation and distribution of oxygen carrying red blood cells within the different organs. The determinants of oxygen delivery, blood flow regulation, tissue oxygen tension, and mitochondrial well-being are not fully understood; however, it is clear that insight into the function of the microcirculation is key in this respect. In fact, it is clear that the origin of circulatory failure in critical illness unresponsive to therapy is not represented in systemic hemodynamic variables but rather in the dysfunction of the microcirculation. The introduction of bedside techniques into clinical practice that allow the evaluation of the microcirculation has opened up a new field of functional hemodynamic monitoring, identified the microcirculatory failure as the most sensitive indicator of circulatory failure associated with adverse outcome, and has provided the promise of identifying new therapeutic targets. Clinical research has identified various conventional and new therapeutic approaches that are successful in modifying the microcirculation. Current research must determine whether some of these approaches are successful in improving the outcome of critically ill patients by recruiting the microcirculation. Read the Abstract in PubMed
Shock. 2010 Apr;33(4):387-91 || Conclusions: Efforts to improve survival from sepsis are focusing increasingly on intervention during the earliest stages of this disease. The importance of derangements in microvascular flow in patients with established sepsis is well recognized. However, little data are available to describe microvascular changes in early sepsis. After research ethics committee approval, observational data were collected in healthy volunteers and within 6 h of presentation in patients with sepsis and severe sepsis. Sidestream dark-field imaging was used to obtain video images of the sublingual microcirculation. Cardiac index was measured using the noninvasive suprasternal Doppler method. Forty-eight patients and 16 healthy volunteers were recruited. Twenty-eight patients were diagnosed with sepsis and 19 with severe sepsis. Eight patients (17%) did not survive to leave hospital. For small vessels (<20 microm), microvascular flow index (P < 0.05), heterogeneity index (P < 0.05) and the proportion of perfused vessels (P < 0.05) were lower in patients with sepsis and severe sepsis compared with healthy volunteers. Perfused vessel density (P < 0.05) was lower in the severe sepsis group compared with the sepsis group. The proportion of perfused vessels (P < 0.01) and MAP (P < 0.05) were lower in nonsurvivors compared with survivors. Sepsis results in derangements of microvascular flow, which can be identified in the early stages of this disease. These abnormalities are more marked in the most severely ill patients. Further research is required to fully characterize the effects of sepsis on microvascular function.
J Crit Care. 2012 Oct;27(5):531.e1-7 || Conclusions: In this cohort of patients with hemodynamic instability, we observed discordance between microcirculatory blood flow and arterial pressure. These data support the concept that microcirculatory blood flow indices can yield physiologic information distinct from macrocirculatory hemodynamic parameters. Read the abstract in PubMed